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Routes of Exposure – Skin
 Penetration Studies
 
Robert L. Bronaugh, Ph.D.
Director, Cosmetic Staff
Office of Cosmetics and Colors, FDA
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nCollaborative pro= jects with NCTR/NTP and the University of Maryland <= span style=3D'position:absolute;top:45.5%;left:16.66%;width:79.96%;height:6.74%= '>nOther = studies of nanoparticles and skin penetration
<= span style=3D'visibility:hidden'>n
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NNI Definition of Nanotechnology
nAt least one dimension of the product is in the length scale range of approximately 1-100 nm. nStructures, de= vices, and systems have novel properties and functions because= of their small size nThere is the a= bility to control or manipulate the product on the atomic scale<= /b>
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Possible Uses of Nanotechnology
in Cosmetics
nNanodispersed systems
uLiposomes (nanosomes)
uNanoemulsion
uSolid lipid nanoparticles
nOther Nanoparticles
uPolymer systems
uMetal oxide nanoparticles
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Quantum Dot Study
Model compound for topically applied  products
● Relatively stable
● Highly fluorescent
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